Genetic risks of developing diseases
NewsFrom a genetic point of view, all diseases can be divided into:
– chromosomal – associated with quantitative or structural changes in chromosomes;
– monogenic – associated with a defect in one particular gene;
– polygenic -– associated with changes in various genes in combination with the influence of external environmental provoking factors.
It is worth noting that monogenic diseases are inherited according to the laws of Mendel, namely:
– autosomal dominant;
– autosomal recessive;
– X-linked-dominant;
– X-linked recessive;
– Y-linked;
– in addition, some diseases associated with mutations of extra-nuclear DNA can be transmitted by mitochondrial type.
Each of these types of inheritance is characterized by a special distribution of sick and healthy family members in the pedigree. In some cases, the disease can be transmitted vertically from generation to generation with a 50% probability (autosomal dominant type). In other cases, only males in the family suffer (X-linked recessive type), etc.
In the Center for Personalized Medicine of the MCSC named after A.S. Loginov, you can get a comprehensive assessment of the state of health, including psychological factors, learn about predispositions to diseases, and get personalized treatment depending on the genotype.
During the consultation process, the geneticist determines the type of inheritance of the disease in the family of the applicant and determines the risk of transmitting the disease to the next generation.
A high genetic risk is considered to be a risk exceeding 20%.
Detailed information:
+7-495-304-30-39 | +7-905-525-50-05
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