Treatment of pseudomembranous colitis after COVID-19. MCSC patient history
NewsA 63-year-old patient was admitted to the MCSC in a serious condition . This hospitalization was not his first this year.
- He had previously suffered fromCOVID-19, which was treated with antibiotics and cytokine storm blockers.
- During the course of the disease, like 20% of all COVID-19 patients, the patient complained of diarrhea, but after recovery, the stool did not return to normal.
The diarrhea persisted, so the patient was hospitalized again. The results of the examination revealed that toxins A and B of the bacterium Clostridium difficile were found in the feces.
- After treatment, he was discharged with a temporary improvement.
Pseudomembranous colitis is an inflammation of the colonthat is most often caused by the toxigenic bacterium Clostridium difficile.
- Its characteristic feature is fibrinous overlays on the mucous membrane of the colon and diarrhea.
It should be noted that a quarter of patients after conservative treatment of clostridial pseudomembranous colitis have a relapse of the disease.
So, after some time, our patient's pseudomembranous colitis developed with a new force.
- Diarrhea grew, and fever and abdominal pain joined in.
- Diarrhea led to severe water-electrolyte disorders, the development of hypoalbuminemia – the patient's condition deteriorated markedly.
With such clinical, laboratory and instrumental data, death could occur with a 46% probability.
In addition, against the background of multicomponent conservative therapy, the patient developed toxic dilatation of the colon.
- The doctors decided to perform the operation. At the same time, there was a high risk of death (up to 80%).
- Thus, a favorable outcome of the disease in our patient was unlikely.
Surgeons urgently performed a colectomy-removed the large intestine with the formation of a small bowel stoma.
The postoperative period was uneventful, and the patient was soon discharged from the Coloproctology department of the MCSC.
- And after a while, he returned to his usual way of life.
The well-coordinated work of the MCSC team-anesthesiologists, resuscitators, gastroenterologists, coloproctologists, as well as the patient's will to recover – allowed us to successfully cure the fulminant form of pseudomembranous colitis, complicated by toxic dilatation of the colon against the background of a coronavirus infection.
