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Desmoid fibroids. MCSC patient history


The MCSC was contacted by patient N., 50 years old.

She was worried about:

  • loose stools up to 6-7 times a day, sometimes with an admixture of blood and mucus,
  • unpleasant sensations in the lower abdomen. 

She said that in August 2022 she underwent antibacterial therapy due to exacerbation of bronchitis, and then she had loose stools up to 5 times a day and bloating. 

After the examination, doctors ruled out intestinal infections. But since these symptoms appeared after treatment, experts suggested that it could be pseudomembranous colitis.

  • This is a disease of the colon, in which inflammation occurs and white-yellow plaques form. They are a pseudomembrane on the surface of the intestinal mucosa.

As a result, the patient was admitted to the MCSC Department of Intestinal Pathology to clarify the diagnosis and treatment.

She underwent a comprehensive examination:

  • there are no changes in blood tests
  • toxins A and B of Clostridium difficile were found in feces
  • on ultrasound of the intestine, there are no inflammatory changes in the small and large intestine
  • According to the results of colonoscopy, pathological changes in the colon and ileum were also not detected.

After the woman was prescribed therapy, which helped. 

  • However, the control ultrasound revealed the formation of the abdominal cavity, possibly in the small intestine.  

The analysis for tumor markers turned out to be negative. Then the patient underwent MSCT-enterography, where the presence of a tumor was also confirmed


To clarify the diagnosis and determine the treatment tactics, our specialists also performed endosonography. As a result, the most likely diagnosis was a tumor of the small intestine (leiomyosarcoma or gastrointestinal stromal tumor).

After all the studies, MCSC doctors conducted a multidisciplinary consultation with oncologists, surgeons and radiotherapists. 

  • A decision was made about the operation

Surgeons of the Department of High-tech surgery and surgical endoscopy performed laparoscopic resection of the jejunum. 

In the future, immunohistochemical examination made it possible to make an accurate diagnosis: desmoid fibromatosis – desmoid fibroids.

These are rare connective tissue tumors that occur in only 0.03% of cases among all neoplasms and in less than 3% of all soft tissue tumors. 

  • Most often they occur in patients from 15 to 60 years, somewhat more in women.

Experts consider the main risk factors to be:

  • familial adenomatous polyposis is a genetic disease (5-15%)
  • pregnancy
  • heredity (occurrence of desmoid in relatives)

Fibroids are characterized by aggressive growth, but do not metastasize.

  • They usually manifest as a painless or very minimally painful formation with a slow growth rate. 
  • Sometimes nausea, vomiting, intestinal obstruction, a feeling of rapid satiety, etc. may occur.

The main method of treatment is surgical. 

Today the patient feels well and has returned to her usual life.

  • With a control MSCT one year after the operation, there are no signs of formations, any changes and relapse.

MCSC uses a multidisciplinary approach in the treatment of each patient, and in this case it was thanks to a properly constructed examination plan, a quick and accurate diagnosis that it was possible to identify a rare disease in the shortest possible time.

We are always ready to assist in the treatment of this disease!

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GBUZ Moscow Clinical Scientific Center named after Loginov MHD