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Autoimmune pancreatitis in a patient with ulcerative colitis. MCSC patient history

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Patient P., 22 years old, has been observed at the MCSC named after A.S. Loginov since December 2020 with a diagnosis of ulcerative colitis. He regularly took medication, against the background of which he felt good – abdominal pain did not bother, there were no problems with the stool.

In December 2021, he had an attack of acute pancreatitis. A man with abdominal pain, nausea and vomiting was taken by ambulance to the hospital. In blood tests, an increase in pancreatic enzymes was noted. The hospital doctors prescribed therapy, which allowed to normalize the patient's condition. However, after being discharged home, the man continued to note abdominal pain.

In January 2022, the patient felt unwell. He was hospitalized in the department of treatment of inflammatory bowel diseases of the MCSC named after A.S. Loginov with exacerbation of ulcerative colitis.  During colonoscopy, experts found that there are ulcerative defects of the mucous membrane throughout the colon. The man was prescribed medication, but after 6 hours from the start of taking the drug, he had complaints of nausea, vomiting, severe abdominal pain. In this regard, the doctors took blood tests again, and also consulted the gastroenterologist of the Department of pancreatic pathology and the surgeon of the Department of hepatobiliary surgery. An attack of acute pancreatitis has been confirmed again.

A follow-up examination was prescribed, according to the results of which a diagnosis of type 2 autoimmune pancreatitis was established. Taking into account the high activity of ulcerative colitis and concomitant autoimmune disease of the pancreas, the specialists of our Center have selected the optimal drug therapy. Thanks to her, it was possible to stop the exacerbation of the disease and achieve remission.

6 months after treatment, the patient was invited to a follow-up examination, which confirmed the normalization of the body's condition:

  • During colonoscopy, minimal activity of ulcerative colitis is noted – single lesions of the mucous membrane of the colon.
  • CT scan of the pancreas revealed no organ changes.

Today, the patient continues to be observed in our Center and leads an active lifestyle.


The described clinical case is a rare combination of ulcerative colitis and autoimmune pancreatitis. Ulcerative colitis is most common in patients with type 2 autoimmune pancreatitis. In turn, according to the world literature, ulcerative colitis is detected in 16% of cases in patients with established autoimmune pancreatitis. 

The presented patient history demonstrates the need for constant monitoring by gastroenterologists of patients with ulcerative colitis. Doctors of the IBD treatment department of MCSC regularly monitor patients with ulcerative colitis and Crohn's disease, thus not only controlling the course of the disease, but also timely detecting damage to other organs, which is often observed in patients with IBD. Proper diagnosis allows timely correction of therapy, avoiding complications and improving the quality of life of each patient.

Make an appointment for a consultation with an enterologist:8 (800) 234-24-22

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GBUZ Moscow Clinical Scientific Center named after Loginov MHD